Five tries proved to be enough to ensure that Loughborough Students came away from Priory Park with a crucial five points to pull them away from the drop.
The Students got the first try of the game after going behind early on to a Tom Eaton penalty. Henry Taylor created space around the fringe and put fly half Josh Sharp into space to dive in for the try.
On 12 minutes Rhys Owen extended the visitors lead, a long spell on The Blues try line paid off and The Students soon got over the whitewash.
David Marwick was sent to the bin for Macclesfield on 18 minutes and Loughborough took advantage from the resulting line out to barge their way over the line, Adam Peters with the try, 3-15.
With Marwick back on the field, The Students were reduced to 14 themselves and The Blues got back into the game, a dominant scrum resulted in Liam Parfitt diving over the line, 8-15.
Macc pulled themselves level with a converted try. Winger Josh Fowles bounced off the tackles and dived over the line.
Macclesfield came out after half time and dominated possession and territory until fly half Sam James and prop Marshall Gadd went down to injury.
Loughborough took full advantage of the Macclesfield reshuffle as Rhys Owen dived over to secure his brace. The Students added a penalty shortly after and made it 15-25.
On 72 minutes Henry Taylor spotted a gap around the fringe and touched down under the posts. Ollie Williams then added a penalty, 15-35.
On 78 minutes Matt King crossed for The Blues and gave hope of achieving a late bonus point, but it wasn’t to be as Loughborough came away with the spoils, 22-35.